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Cruises of Royal Caribbean in Panama

  • 2025
  • 2026
  • 2027
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78 cruises

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,221
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 11 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,214
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 18 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,221
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 25 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,131
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 1 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from £1,047
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 8 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,057
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 15 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,051
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 22 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from £1,048
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 29 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £956
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 6 Dec 2025
Duration: 6 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,231
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 12 Dec 2025
Duration: 8 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. navigation,
3. Cartagena De Indias,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. Willemstad,
8. navigation,
9. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,074
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 20 Dec 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Willemstad,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,457
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 27 Dec 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £883
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 3 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,007
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 10 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,024
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 17 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £941
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 24 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £938
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 31 Jan 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £848
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 7 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £939
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 14 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £810
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 21 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £847
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 28 Feb 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £847
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 7 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £845
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 14 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £845
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 21 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,089
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 28 Mar 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Kralendijk,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £970
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 4 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £972
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 11 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon
sold out

Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £759
price per person Taxes included
Serenade Of The Seas | 18 Apr 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Central America: Panama, Costa Rica, Mexico, United States

Colon Itinerary Central America
from £1,107
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 25 Apr 2026
Duration: 10 nights
Departure from: Colon Landing: Los Angeles
Itinerary:
1. Colon,
2. navigation,
3. navigation,
4. Puntarenas,
5. navigation,
6. Huatulco,
7. navigation,
8. Puerto Vallarta,
9. navigation,
10. navigation,
11. Los Angeles

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £843
price per person Taxes included
See the cruise Book Online Book Online
Jewel Of The Seas | 9 May 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon
78 cruises