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Departure calendar Panama

Choose your next cruise departing from the main ports in Panama, your new vacation by the sea is getting closer!

  • 2025
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  • 2027
May 2025 June 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025
January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026
January 2027 February 2027 March 2027 April 2027

Cruises in Panama

109 cruises
sold out

Panama, Spain, United States

Balboa Itinerary Mediterranean
from £3,115
price per person Taxes included
Silver Shadow | 20 May 2025
Duration: 7 nights
Departure from: Balboa Landing: Fort Lauderdale
Itinerary:
1. Balboa,
4. Cartagena ,
8. Fort Lauderdale

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,221
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 11 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,214
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 18 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from £1,221
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 25 Oct 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from £1,131
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 1 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Central America: Panama, Costa Rica

Panama City Itinerary Central America
from £6,133
price per person Taxes included
See the cruise Book Online Book Online
Hanseatic Inspiration | 8 Nov 2025
Duration: 10 nights
Departure from: Panama City Landing: Colon
Itinerary:
1. Panama City,
3. Quepos,
4. navigation,
5. Puntarenas,
7. Playa Panama,
8. Panama Canal,
10. Colon,
11. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from £1,047
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | 8 Nov 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon
109 cruises

All ships passing through Panama

Browse the list of ships with a scheduled stop in Panama, your next cruise is already here.

  • Featured ships
  • Other ships
Jewel Of The Seas Images of Jewel Of The Seas Serenade Of The Seas Images of Serenade Of The Seas Explora III Images of Explora III Azamara Quest Images of Azamara Quest Star Clipper Images of Star Clipper Star Pride Images of Star Pride Wind Spirit Images of Wind Spirit Wind Star Images of Wind Star
Insignia Marina Nautica Regatta Seabourn Encore Seven Seas Grandeur Seven Seas Splendor Le Champlain Hanseatic Inspiration

Panama: Ports of departure

Choose the port in Panama that is most convenient for you and get ready for your dream cruise to the most iconic destinations in the region.

  • Featured ports
  • Other ports
Balboa Images of Balboa Colon Images of Colon Panama City Images of Panama City